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Forskning 

 

Hjerteseksjonen ved SSA driver omfattende klinisk forskning. Hovedmålet med vår forskning er å øke kunnskapen om hjertesykdommer, for å forbedre forebygging, diagnostikk og behandling. Forskningen skjer i nært samarbeid med Oslo Universitetssykehus Rikshospitalet og Universitetet i Oslo. Vi har omfattende forskning innen bruk av avansert hjerteultralyd (ekkokardiografi) hos pasienter med hjerteinfarkt og kransåresykdom.  Vi har også en stor behandlingsstudie som vurderer effekten av å redusere risikofaktorer hos personer med hjertesykdom. I tillegg deltar vi i flere studier som ser på nytten av nye hjertemedisiner.

 

Hjerteseksjonen har tre leger med medisinsk doktorgrad og to doktorgradsstipendiater. Vi har de siste årene publisert en rekke viktige artikler i internasjonale fagtidsskrifter og hatt mange presentasjoner på internasjonale hjertekongresser.

 

Publiserte originalartikler:

  1. Grenne B, Eek C, Sjøli B, Dahlslett T, Hol PK, Ørn S, Skulstad H, Smiseth OA, Edvardsen T, Brunvand H. Prediction of Infarct-size by the Area under the Strain Curve. J Am Soc Echocardiogr. 2011 24:1118-25.
  2. Eek C, Grenne B, Brunvand H, Aakhus S, Endresen K, Smiseth OA, Edvardsen T, Skulstad H. Postsystolic shortening is a strong predictor of recovery of systolic function in patients with non-ST-elevation myocardial infarction. Eur J Echocardiogr. 2011 12:483-9.
  3. Sjøli B, Grenne B, Smiseth OA, Edvardsen T, Brunvand H. The Advantage of Global Strain compared to Left Ventricular Ejection Fraction to predict Outcome after Acute Myocardial Infarction. Echocardiography. 2011;28: 556-63.
  4. Grenne B, Eek C, Sjøli B, Dahlslett T, Uchto M, Hol PK,  Skulstad H, Aakhus S, Smiseth OA, Edvardsen T, Brunvand H. Acute coronary occlusion in non-ST-elevation acute coronary syndrome: outcome and early identification by strain echocardiography. Heart. 2010;96: 1550-6.
  5. Grenne B, Eek C, Sjøli B, Skulstad H, Aakhus S, Smiseth OA, Edvardsen T, Brunvand H. Changes of Myocardial Function in Patients with Non-ST-Elevation Acute Coronary Syndrome Awaiting Coronary Angiography. Am J Cardiol. 2010;105: 1212-8.
  6. Eek C, Grenne B, Brunvand H, Aakhus S, Endresen K, Hol PK, Smith HJ, Smiseth OA, Edvardsen T, Skulstad H. Strain Echocardiography and Wall Motion Score Index Predicts Final Infarct Size in Patients with Non ST Segment Elevation Myocardial Infarction. Circ Cardiovasc Img. 2010;3: 187-94.
  7. Eek C, Grenne B, Brunvand H, Aakhus S, Endresen K, Smiseth OA, Edvardsen T, Skulstad H. Strain echocardiography predicts acute coronary occlusion in patients with non-ST-segment elevation acute coronary syndrome. Eur J Echocardiogr. 2010;11: 501-8.
  8. Sjøli B, Ørn S, Grenne B, Vartdal T, Smiseth OA, Edvardsen T, Brunvand H. Comparison of Left Ventricular Ejection Fraction and Left Ventricular Global Strain as Determinants of Infarct Size in Patients with Acute Myocardial Infarction. J Am Soc Echocardiogr. 2009;22: 1232-8.
  9. Sjøli B, Ørn S, Grenne B, Ihlen H, Edvardsen T, Brunvand H. Diagnostic Capability and Reproducibility of Strain by Doppler and by Speckle Tracking in Patients with Acute Myocardial Infarction. J Am Coll Cardiol Img. 2009;2: 24-33.
     

 

Presentasjoner på internasjonale kongresser:

  1. Haugaa KH, Grenne B, Voigt JU, Svendsen JH, Eek CH, Sjøli B, Desmet W,  Brunvand H, Smiseth OA, Edvardsen T. Global strain by echocardiography is superior to ejection fraction to predict ventricular arrhythmias after myocardial infarction. American Heart Association Scientific Sessions 2011, Orlando, FL.
  2. Haugaa KH, Grenne B, Voigt JU, Svendsen JH, Eek CH, Sjøli B, Desmet W,  Brunvand H, Smiseth OA, Edvardsen T. Mechanical dispersion predicts ventricular arrhythmias after myocardial infarction in patients with ejection fraction better than 35%.. American Heart Association Scientific Sessions 2011, Orlando, FL.
  3. Dahlslett T, Grenne B, Eek C, Sjøli B, Skulstad H, Smiseth O, Edvardsen T, Brunvand H. Early Strain Echocardiography May Exclude Significant Coronary Artery Stenosis in Suspected Non-ST-Elevation Acute Coronary Syndrome. American Heart Association Scientific Sessions 2011, Orlando, FL.
  4. Grenne B, Eek C, Sjøli B, Dahlslett T, Hol PK, Ørn S, Skulstad H, Smiseth OA, Edvardsen T, Brunvand H. The Area under the Strain Curve Provides Early Prediction of Infarct Size in Patients with Acute Myocardial Infarction. American College of Cardiology Annual Scientific Session 2011, New Orleans, LA.
  5. Dahlslett T, Helland I, Edvardsen T, Skulstad H. The influence of juvenile neuronal ceroid lipofuscinosis on the left ventricle. European Association of Echocardiography annual meeting 2010, Copenhagen.
  6. Grenne B, Eek C, Sjøli B, Dahlslett T, Uchto M, Hol PK, Skulstad H, Smiseth OA, Edvardsen T, Brunvand H. Circumferential Strain by Echocardiography Identifies Acute Occlusions in Non ST-elevation Acute Coronary Syndromes. European Society of Cardiology Congress 2010, Stockholm.
  7. Grenne B, Eek C, Sjøli B, Dahlslett T, Hol PK, Skulstad H, Smiseth OA, Edvardsen T, Brunvand H. A simplified 6 segments model of circumferential strain by echocardiography reflects LV infarct size in NSTEMI European Society of Cardiology Congress 2010, Stockholm.
  8. Grenne B, Eek C, Sjøli B, Dahlslett T, Uchto M, Hol PK, Skulstad H, Smiseth OA, Edvardsen T, Brunvand H. Impaired Outcome with Acute Coronary Occlusions in Non-ST-Elevation Myocardial Infarction. American College of Cardiology Annual Scientific Session 2010, Atlanta, GA.
  9. Eek C, Grenne B, Brunvand H, Aakhus S, Endresen K, Smiseth OA, Edvardsen T, Skulstad H. Postsystolic shortening demonstrates viability in patients with acute non ST-segment elevation myocardial infarction. EuroEcho 2009, Madrid.
  10. Sjøli B, Ørn S, Grenne B, Vardal T, Smiseth OA, Edvardsen T, Brunvand H. Comparison of Left Ventricular Global Strain and Left Ventricular Ejection Fraction as Determinants of Left Ventricular Injury in Patients with Acute Myocardial Infarction. European Society of Cardiology Congress 2009, Barcelona.
  11. Eek C, Grenne B, Hol PK, Smith HJ, Aakhus S, Brunvand H, Smiseth OA, Edvardsen T, Skulstad H. Global strain is a strong predictor of infarct size in patients hospitalized with NSTEMI. European Society of Cardiology Congress 2009, Barcelona.
  12. Sjøli B, Ørn S, Grenne B, Edvardsen T, Brunvand H. Circumferential Strain Is Superior to Longitudinal Strain to Separate Subendocardial From Transmural Necrosis. American College of Cardiology Annual Scientific Session 2009, Orlando, Fla.
  13. Grenne B, Eek C, Sjøli B, Skulstad H, Aakhus S, Smiseth OA, Edvardsen T, Brunvand H. Deterioration of Left Ventricular Function in patients with Non-ST-Elevation Myocardial Infarction Awaiting Coronary Angiography. American College of Cardiology Annual Scientific Session 2009, Orlando, Fla.
  14. Eek C, Grenne B, Brunvand H, Aakhus S, Endresen K, Smiseth OA, Edvardsen T, Skulstad H. Strain and strain rate by speckle tracking echocardiography predicts coronary occlusion in NSTE-ACS. European Society of Cardiology Congress 2008, Munich.
  15. Sjøli B, Ørn S, Grenne B, Vartdal T, Ihlen H, Edvardsen T, Brunvand H. Which strain method can best predict infarct size in acute myocardial infarction - strain by Doppler or speckle tracking echocardiography? European Society of Cardiology Congress 2007, Vienna.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Publisert 02.02.2012 09:44 | Endret 02.02.2012 17:32 

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